LesionQuant

  • Automatically quantifies brain structures and segmental lesions from MRI studies, improving the ability to identify and monitor the number and progression of brain lesions.

  • It uses a T2 FLAIR sequence, in addition to the 3D T1 sequence, which provides data for identifying brain lesions associated with T2 FLAIR hyperintensities.

  • Longitudinal reports allow you to monitor lesion volume and visually assess changes by overlapping color-coded FLAIR lesion when previous scan data is available.

  • It allows to obtain lesion volume (cm³), count and percentage of intracranial volume for all lesions and is further classified into total lesions, new lesions and enlarged lesions:

  1. Total Injuries Cover All Current, New, and Increased Injuries

  2. New lesions are defined as areas of intensity that were not present in previous acquisition images.

  3. Enlarged lesions are defined as lesions present in previous acquisition images and increased by 20% over previous images.

  4. Touching lesions are counted / considered as an injury.

Benefits

  • Assume lesions as separate when the distance between them is greater than one voxel or about 1 mm. This lesion separation threshold may be increased in 1 mm increments with a range of 1-5 mm;

  • In 5-7 minutes, results are available for review in PACS;

  • The minimum lesion size setting has a range of 1 to 64 mm³ to meet diagnostic needs;

  • Detection limits follow McDonald's Criteria for Space Dissemination and may be defined separately for leucocortical, periventricular, infratentorial and deep white matter regions;

  • You can set thresholds for each region in an artificial range from 0 to 2 (1 is the default value). Lowering a threshold below 1 increases detection sensitivity while increasing sensitivity (ie 0 is the most sensitive setting, potentially allowing detection of more lesions, but also increasing the risk of false positives and 2 is the least sensitive allowing potentially fewer false positives, but also increasing the risk of missing injuries).